Jessica Lang

Contact Information

kueck@wisc.edu
608-262-8601
2766 Wisconsin Institute for Medical Research

Education

BS, 2009, Genetics, University of Wisconsin-Madison
PhD, 2014, Cancer Biology, University of Wisconsin-Madison
Postdoctoral Research, Arizona State University and TGen (Translational Genomics Research Institute)

Title

Assistant Professor of Pathology and Laboratory Medicine

Research Description

My scientific mission is to leverage genomics and epigenetics in ovarian cancer (OvCa) models to produce translational and impactful science building on my research in somatic mutations in chromatin remodeling factors and epigenetic dysfunction through the following research goals: 1) Understand dynamics of epigenetic features following chemotherapy treatment and resistance; 2) Identify potential therapies for treatment that exploit epigenomic features; 3) Integrate epigenomic features with somatic cancer mutations towards a more comprehensive OvCa picture. I will approach these research goals using human cell lines and tumor tissue to identify shared and necessary OvCa enhancers, validated by innovative functional epigenomics approaches and preclinical models. I will also continue my history of scientific collaborations and clinical partnerships to support my research and ensure clinical translation of findings.

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