BS, 1998, Medical Microbiology and Immunology, University of Wisconsin-Madison
PhD, 2006, Pathology, University of Wisconsin-Madison
Department of Pathobiological Sciences
School of Veterinary Medicine
My laboratory focuses on developing innovative tools for investigating and combating human diseases. Our primary area of research is evaluating the virologic and immunologic mechanisms that control AIDS virus replication. We developed a novel model for establishing latent simian immunodeficiency virus (SIV) reservoirs of precise sizes by infusing defined numbers of in vitro generated latently infected cells into SIV-naive rhesus macaques. With this model, we are investigating how latent reservoir size affects an individual’s ability to control virus replication after stopping antiretroviral drug treatment.
Our other research focus is isolating monoclonal antibodies. We developed an efficient method for isolating monoclonal antibodies from memory B cells and employ it to clone antibodies for diagnostic or therapeutic use.
Lab Website: reynolds.labs.wisc.edu