LOCATION: University of Wisconsin-Madison
DESCRIPTION: STEM/PROGENITOR CELL BIOLOGY, CANCER BIOLOGY AND EPIGENETICS
The Bresnick laboratory is recruiting a postdoctoral trainee to work on normal and malignant hematopoiesis, as well as fundamental problems in cellular regulation, including epigenetics. The laboratory is located in the new Wisconsin Institute of Medical Research (WIMR) research facility in the UW School of Medicine and Public Health, which provides a highly collaborative scholarly environment for conducting innovative basic and translational/clinical research.
We use multidisciplinary approaches to understand biological and mechanistic processes, including stem/progenitor cell function, blood cell development, and pathologies including cancer, myelodysplastic syndromes and anemia. These studies involve genomics, proteomics, gene editing, computational analysis, and powerful molecular, cellular, and biochemical methodologies in primary cells and mice. Postdoctoral trainees have ample opportunities to develop high-impact research projects in these areas, gain expertise in fellowship/grant writing, and hone their critical thinking and presentation skills to prepare for careers in academia, private sector or other venues.
Research Topics include:
- Hematopoiesis and Disease Mechanisms. Deviations from hematopoietic programs yield leukemia, lymphoma, myelodysplastic syndromes and anemias. We are analyzing GATA transcription factor mechanisms that suppress or cause pathologies and are using these mechanisms to forge translational/clinical
- Epigenetic Mechanisms and Synthetic We are addressing mechanistic and translational issues in genome biology, e.g. how cis-elements function in chromatin, how genetic networks are established and maintained and how chromatin modification/remodeling regulate transcription of endogenous loci.
The successful candidate shall hold a PhD from an excellent university, have no more than three prior years of postdoctoral experience, have published at least one important first-author paper from their doctoral research and have excellent communication/interaction skills.
Apply via email to: Emery H. Bresnick, Ph.D., firstname.lastname@example.org
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