Contact Information
1111 Highland Ave
Madison WI 53705-2275
Madison WI 53705-2275
Title
Assistant Professor of Hematology, Medical Oncology and Palliative Care
Education
- University of Chicago – MD
- University of Wisconsin Hospital and Clinics – Residency in Internal Medicine
- University of Wisconsin Hospital and Clinics – Fellowship in Medical Oncology (American Board of Internal Medicine’s Research Pathway)
- University of Chicago – PhD in Cancer Biology
- University of Wisconsin Carbone Cancer Center, Madison, Wisconsin – Post-doctoral research, focus on novel technologies for advanced molecular profiling in breast and prostate cancer liquid biopsies
Research Description
The Sharifi lab is focused on identifying molecular mechanisms of targeted therapy resistance in advanced breast and prostate cancer to develop new and more effective therapies. Our research utilizes translational liquid biopsy based approaches and patient derived models to evaluate dynamic changes in endocrine and oncogene signaling that occur in response to estrogen, androgen and PI3K pathway targeted therapies in patients with hormone dependent cancers. The overarching goal of our work is to develop new strategies to overcome targeted therapy resistance through a better understanding of the molecular changes that drive resistance in patients.