Contact Information
Phone:608-265-9645
Address:
WIMR 4153
1111 Highland Avenue
Madison, WI 53705
Education
BS, Ashland University, Ashland, Ohio
PhD, Oregon Health and Science University, Portland, Oregon
MD, Oregon Health and Science University, Portland, Oregon
Residency, Pediatrics, Seattle Children’s Hospital, University of Washington, Seattle, Washington
Fellowship, Pediatric Hematology and Oncology, Stanford University, Stanford, California
Title
Assistant Professor, Department of Pediatrics
Research Description
The Richards lab focuses on developing chimeric antigen receptor T (CAR-T) cell therapy for acute myeloid leukemia (AML), a disease that can be difficult to treat and is associated with many treatment-related toxicities. CAR-T cell therapy has revolutionized treatment for patients with B cell malignancies, and is an attractive option for treatment of AML. Despite promising pre-clinical data, translation to patients has been hampered by tumor heterogeneity and the possibility of on-target, off-tumor toxicity to healthy tissues. The Richards Lab employs cellular engineering to endow CAR T cells with improved tumor specificity, and uses a variety of pre-clinical models to identify critical components of AML tumor cell and CAR-T cell biology that will inform further clinical development.