University of Wisconsin–Madison

New BMC Course Announcement: Fall 2018

BMC 675 From Mutations to Mechanisms Fall Semester, 2018 11:00-11:50 AM Tuesday and Thursday 2321 Biochemical Sciences Building

Instructors: Heidi Dvinge, Melissa Harrison, Peter Lewis High-throughput sequencing technologies are identifying an increasing number of mutations associated with human diseases. Interpreting such mutations and dissecting the mechanism by which they contribute to disease phenotypes remain challenging This 2-credit course will explore laboratory and computational methodologies involved in the interpretation of genomic data. The goal will be to evaluate and use genomic datasets to explore molecular mechanisms using various laboratory model systems. Topics will include strategies and techniques for genomic data interpretation, introduction to precision medicine, genome-wide association studies, genomics for disease prediction, and use of model systems to investigate the underlying mechanism. Text: Research literature Prerequisites: BIOCHEM 620 Eukaryotic Molecular Biology For information: contact Peter Lewis, phone 316-4388, peter.lewis@wisc.edu